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Microglial cell response in α7 nicotinic acetylcholine receptor-deficient mice after systemic infection with Escherichia coli

BACKGROUND: Development of neurodegeneration in older people has been associated with microglial cell activation triggered by systemic infection. We hypothesize that α7 nicotinic acetylcholine receptor (α7nAChR) plays an important role in regulation of this process. METHODS: 8- to 10-week-old male w...

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Detalles Bibliográficos
Autores principales: Hoogland, Inge C. M., Yik, Jutka, Westhoff, Dunja, Engelen-Lee, Joo-Yeon, Valls Seron, Merche, Man, Wing Kit, Houben-Weerts, Judith H. P. M., Tanck, Michael W. T., van Westerloo, David J., van der Poll, Tom, van Gool, Willem A., van de Beek, Diederik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006549/
https://www.ncbi.nlm.nih.gov/pubmed/35413868
http://dx.doi.org/10.1186/s12974-022-02452-8