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MFN2 knockdown promotes osteogenic differentiation of iPSC-MSCs through aerobic glycolysis mediated by the Wnt/β-catenin signaling pathway

BACKGROUND: Mitofusin-2 (MFN2) is a kind of GTPase that participates in the regulation of mitochondrial fusion, which is related to a variety of physiological and pathological processes, including energy metabolism, cell differentiation, and embryonic development. However, it remains unclear whether...

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Detalles Bibliográficos
Autores principales: Deng, Lidi, Yi, Siqi, Yin, Xiaohui, Li, Yang, Luan, Qingxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006575/
https://www.ncbi.nlm.nih.gov/pubmed/35413941
http://dx.doi.org/10.1186/s13287-022-02836-w