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Challenges to the broad application of allogeneic natural killer cell immunotherapy of cancer

Natural killer (NK) cells are innate immune cells that recognize malignant cells through a wide array of germline-encoded receptors. Triggering of activating receptors results in cytotoxicity and broad immune system activation. The former is achieved through release of cytotoxic granules and present...

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Detalles Bibliográficos
Autores principales: Kennedy, Philippa R., Felices, Martin, Miller, Jeffrey S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006579/
https://www.ncbi.nlm.nih.gov/pubmed/35414042
http://dx.doi.org/10.1186/s13287-022-02769-4