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Challenges to the broad application of allogeneic natural killer cell immunotherapy of cancer
Natural killer (NK) cells are innate immune cells that recognize malignant cells through a wide array of germline-encoded receptors. Triggering of activating receptors results in cytotoxicity and broad immune system activation. The former is achieved through release of cytotoxic granules and present...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006579/ https://www.ncbi.nlm.nih.gov/pubmed/35414042 http://dx.doi.org/10.1186/s13287-022-02769-4 |