Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones

BACKGROUND: In inherited retinal disorders such as retinitis pigmentosa (RP), rod photoreceptor-specific mutations cause primary rod degeneration that is followed by secondary cone death and loss of high-acuity vision. Mechanistic studies of retinal degeneration are challenging because of retinal he...

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Detalles Bibliográficos
Autores principales: Karademir, Duygu, Todorova, Vyara, Ebner, Lynn J. A., Samardzija, Marijana, Grimm, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006580/
https://www.ncbi.nlm.nih.gov/pubmed/35413909
http://dx.doi.org/10.1186/s12915-022-01280-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006580/
https://www.ncbi.nlm.nih.gov/pubmed/35413909
http://dx.doi.org/10.1186/s12915-022-01280-9

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