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Single-cell RNA sequencing of the retina in a model of retinitis pigmentosa reveals early responses to degeneration in rods and cones
BACKGROUND: In inherited retinal disorders such as retinitis pigmentosa (RP), rod photoreceptor-specific mutations cause primary rod degeneration that is followed by secondary cone death and loss of high-acuity vision. Mechanistic studies of retinal degeneration are challenging because of retinal he...
Autores principales: | Karademir, Duygu, Todorova, Vyara, Ebner, Lynn J. A., Samardzija, Marijana, Grimm, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006580/ https://www.ncbi.nlm.nih.gov/pubmed/35413909 http://dx.doi.org/10.1186/s12915-022-01280-9 |
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