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Chemical genetic activation of the cholinergic basal forebrain hippocampal circuit rescues memory loss in Alzheimer’s disease
BACKGROUND: The degeneration of the cholinergic circuit from the basal forebrain to the hippocampus contributes to memory loss in patients suffering from Alzheimer’s disease (AD). However, the internal relationships between the acetylcholine (Ach) cycle and memory decline during the early stages of...
Autores principales: | Liu, Weilin, Li, Jianhong, Yang, Minguang, Ke, Xiaohua, Dai, Yaling, Lin, Huawei, Wang, Sinuo, Chen, Lidian, Tao, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006585/ https://www.ncbi.nlm.nih.gov/pubmed/35418161 http://dx.doi.org/10.1186/s13195-022-00994-w |
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