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Dapagliflozin, sildenafil and their combination in monocrotaline-induced pulmonary arterial hypertension
BACKGROUND: Dapagliflozin, a selective inhibitor of sodium-glucose cotransporter 2 (SGLT2), can reduce cardiovascular events and mortality in patients with heart failure. A number of mechanisms have been proposed to explain the beneficial effects of SGLT2 inhibitors. The purpose of this study was to...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006601/ https://www.ncbi.nlm.nih.gov/pubmed/35413880 http://dx.doi.org/10.1186/s12890-022-01939-7 |