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LINC00114 stimulates growth and glycolysis of esophageal cancer cells by recruiting EZH2 to enhance H3K27me3 of DLC1

OBJECTIVE: LINC00114 could promote the development of colorectal cancer, but its mechanism has been rarely discussed in esophageal cancer (EC). Herein, we explored the molecular mechanism of LINC00114 via mediating enhancer of zeste homolog 2/deleted in liver cancer 1 (EZH2/DLC1) axis in EC. METHODS...

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Detalles Bibliográficos
Autores principales: Qin, Jianzhang, Li, Yishuai, Li, Zhe, Qin, Xuebo, Zhou, Xuetao, Zhang, Hao, Li, Shujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006613/
https://www.ncbi.nlm.nih.gov/pubmed/35414117
http://dx.doi.org/10.1186/s13148-022-01258-y