Cargando…

LINC00114 stimulates growth and glycolysis of esophageal cancer cells by recruiting EZH2 to enhance H3K27me3 of DLC1

OBJECTIVE: LINC00114 could promote the development of colorectal cancer, but its mechanism has been rarely discussed in esophageal cancer (EC). Herein, we explored the molecular mechanism of LINC00114 via mediating enhancer of zeste homolog 2/deleted in liver cancer 1 (EZH2/DLC1) axis in EC. METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Qin, Jianzhang, Li, Yishuai, Li, Zhe, Qin, Xuebo, Zhou, Xuetao, Zhang, Hao, Li, Shujun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006613/ https://www.ncbi.nlm.nih.gov/pubmed/35414117 http://dx.doi.org/10.1186/s13148-022-01258-y

Ejemplares similares

Long Non-coding RNA LINC00114 Facilitates Colorectal Cancer Development Through EZH2/DNMT1-Induced miR-133b Suppression
por: Lv, Lv, et al.
Publicado: (2019)

EZH2-mediated H3K27me3 inhibits ACE2 expression
por: Li, Yuanyuan, et al.
Publicado: (2020)

Exosomal lncRNA ZFAS1 regulates esophageal squamous cell carcinoma cell proliferation, invasion, migration and apoptosis via microRNA-124/STAT3 axis
por: Li, Zhirong, et al.
Publicado: (2019)

EZH2/H3K27Me3 and phosphorylated EZH2 predict chemotherapy response and prognosis in ovarian cancer
por: Sun, Si, et al.
Publicado: (2020)

FBP1 knockdown decreases ovarian cancer formation and cisplatin resistance through EZH2-mediated H3K27me3
por: Xiong, Xifeng, et al.
Publicado: (2022)

EZH2-Mediated H3K27me3 Targets Transcriptional Circuits of Neuronal Differentiation
por: Buontempo, Serena, et al.
Publicado: (2022)

LINC00673 Represses CDKN2C and Promotes the Proliferation of Esophageal Squamous Cell Carcinoma Cells by EZH2-Mediated H3K27 Trimethylation
por: Zhou, Menghan, et al.
Publicado: (2020)

Epigenetic drift of H3K27me3 in aging links glycolysis to healthy longevity in Drosophila
por: Ma, Zaijun, et al.
Publicado: (2018)

LncRNA-BLACAT1 Facilitates Proliferation, Migration and Aerobic Glycolysis of Pancreatic Cancer Cells by Repressing CDKN1C via EZH2-Induced H3K27me3
por: Zhou, Xin, et al.
Publicado: (2020)

EZH2 dependent H3K27me3 is involved in epigenetic silencing of ID4 in prostate cancer
por: Chinaranagari, Swathi, et al.
Publicado: (2014)

Remarkable Synergy When Combining EZH2 Inhibitors with YM155 Is H3K27me3-Independent
por: Yang, Jun, et al.
Publicado: (2022)

EZH2-mediated H3K27me3 is a predictive biomarker and therapeutic target in uveal melanoma
por: Hou, Chen, et al.
Publicado: (2022)

EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis
por: Verma, Ayushi, et al.
Publicado: (2022)

Androgens regulate ovarian gene expression by balancing Ezh2-Jmjd3 mediated H3K27me3 dynamics
por: Roy, Sambit, et al.
Publicado: (2021)

Curcumin inhibits the growth of triple‐negative breast cancer cells by silencing EZH2 and restoring DLC1 expression
por: Zhou, Xueliang, et al.
Publicado: (2020)

LINC00665 Induces Acquired Resistance to Gefitinib through Recruiting EZH2 and Activating PI3K/AKT Pathway in NSCLC
por: Liu, Xinyin, et al.
Publicado: (2019)

Ezh2 mediated H3K27me3 activity facilitates somatic transition during human pluripotent reprogramming
por: Rao, Radhika Arasala, et al.
Publicado: (2015)

Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3
por: Yu, Yongxin, et al.
Publicado: (2018)

Inhibition of EZH2 Promotes Human Embryonic Stem Cell Differentiation into Mesoderm by Reducing H3K27me3
por: Yu, Yongxin, et al.
Publicado: (2017)

H3K27me3 and EZH2 expression in melanoma: relevance for melanoma progression and response to immune checkpoint blockade
por: Hoffmann, Friederike, et al.
Publicado: (2020)

Role of EZH2-mediated H3K27me3 in placental ADAM12-S expression: implications for fetoplacental growth
por: Zhu, Ya-nan, et al.
Publicado: (2022)

The EZH2-H3K27me3 axis modulates aberrant transcription and apoptosis in cyclophosphamide-induced ovarian granulosa cell injury
por: Chen, Yingyan, et al.
Publicado: (2023)

Long Non-coding RNA LINC-PINT Suppresses Cell Proliferation and Migration of Melanoma via Recruiting EZH2
por: Xu, Yangfan, et al.
Publicado: (2019)

Inhibition of cytoplasmic EZH2 induces antitumor activity through stabilization of the DLC1 tumor suppressor protein
por: Tripathi, Brajendra K., et al.
Publicado: (2021)

EZH2 Regulates ANXA6 Expression via H3K27me3 and Is Involved in Angiotensin II-Induced Vascular Smooth Muscle Cell Senescence
por: Li, Yuejin, et al.
Publicado: (2022)

EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers
por: Au, Sandy Leung-Kuen, et al.
Publicado: (2013)

The EZH2–PRC2–H3K27me3 axis governs the endometrial cell cycle and differentiation for blastocyst invasion
por: Fukui, Yamato, et al.
Publicado: (2023)

Interplay of miR-137 and EZH2 contributes to the genome-wide redistribution of H3K27me3 underlying the Pb-induced memory impairment
por: Gu, Xiaozhen, et al.
Publicado: (2019)

Cantharidin suppresses hepatocellular carcinoma development by regulating EZH2/H3K27me3-dependent cell cycle progression and antitumour immune response
por: Yan, Jia, et al.
Publicado: (2023)

Correction: EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers
por: Au, Sandy Leung-Kuen, et al.
Publicado: (2014)

Prognostic implications of polycomb proteins ezh2, suz12, and eed1 and histone modification by H3K27me3 in sarcoma
por: Cho, Yong Jin, et al.
Publicado: (2018)

Azithromycin attenuates wheezing after pulmonary inflammation through inhibiting histone H3K27me3 hypermethylation mediated by EZH2
por: Wu, Shuqi, et al.
Publicado: (2023)

miR‐493 by regulating of c‐Jun targets Wnt5a/PD‐L1‐inducing esophageal cancer cell development
por: Bian, Wei, et al.
Publicado: (2021)

Functional analysis of the Drosophila RhoGAP Cv-c protein and its equivalence to the human DLC3 and DLC1 proteins
por: Sotillos, Sol, et al.
Publicado: (2018)

EZH2-H3K27me3-mediated silencing of mir-139-5p inhibits cellular senescence in hepatocellular carcinoma by activating TOP2A
por: Wang, Ke, et al.
Publicado: (2023)

Quantification of Histone H3 Lys27 Trimethylation (H3K27me3) by High-Throughput Microscopy Enables Cellular Large-Scale Screening for Small-Molecule EZH2 Inhibitors
por: Luense, Svenja, et al.
Publicado: (2015)

Long noncoding RNA NEAT1 suppresses hepatocyte proliferation in fulminant hepatic failure through increased recruitment of EZH2 to the LATS2 promoter region and promotion of H3K27me3 methylation
por: Wang, Qiang, et al.
Publicado: (2020)

PRC2 recruitment and H3K27me3 deposition at FLC require FCA binding of COOLAIR
por: Tian, Yongke, et al.
Publicado: (2019)

Prognostic Value of Polycomb Proteins EZH2, BMI1 and SUZ12 and Histone Modification H3K27me3 in Colorectal Cancer
por: Benard, Anne, et al.
Publicado: (2014)

Astronauts Plasma-Derived Exosomes Induced Aberrant EZH2-Mediated H3K27me3 Epigenetic Regulation of the Vitamin D Receptor
por: Bisserier, Malik, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_44pgreh3mb3lupt3uetspc3ubg