Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX1

BACKGROUND: Chronic morphine exposure induces immunosuppression in the peripheral and central nervous system, resulting in susceptibility of patients to invading pathogens. Mitophagy is a crucial regulator of inflammation, and dysregulated mitophagy may cause immunosuppression, but whether mitophagy...

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Detalles Bibliográficos
Autores principales: Peng, Jialing, Pan, Jingrui, Wang, Hongxuan, Mo, Jingjing, Lan, Lihuan, Peng, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006625/
https://www.ncbi.nlm.nih.gov/pubmed/35414088
http://dx.doi.org/10.1186/s12974-022-02453-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006625/
https://www.ncbi.nlm.nih.gov/pubmed/35414088
http://dx.doi.org/10.1186/s12974-022-02453-7

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