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Morphine-induced microglial immunosuppression via activation of insufficient mitophagy regulated by NLRX1
BACKGROUND: Chronic morphine exposure induces immunosuppression in the peripheral and central nervous system, resulting in susceptibility of patients to invading pathogens. Mitophagy is a crucial regulator of inflammation, and dysregulated mitophagy may cause immunosuppression, but whether mitophagy...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006625/ https://www.ncbi.nlm.nih.gov/pubmed/35414088 http://dx.doi.org/10.1186/s12974-022-02453-7 |