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Click chemistry and optogenetic approaches to visualize and manipulate phosphatidic acid signaling

The simple structure of phosphatidic acid (PA) belies its complex biological functions as both a key phospholipid biosynthetic intermediate and a potent signaling molecule. In the latter role, PA controls processes including vesicle trafficking, actin dynamics, cell growth, and migration. However, e...

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Detalles Bibliográficos
Autores principales: Tei, Reika, Baskin, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006657/
https://www.ncbi.nlm.nih.gov/pubmed/35276134
http://dx.doi.org/10.1016/j.jbc.2022.101810