Metformin improves renal injury of MRL/lpr lupus-prone mice via the AMPK/STAT3 pathway

OBJECTIVE: Lupus nephritis (LN) is a major complication and cause of death among patients with SLE. This research used in vivo and in vitro experiments to explore the therapeutic potential of metformin in kidney injury from LN-induced inflammation. METHODS: In vivo study, 8-week-old MRL/MpJ-Faslpr/J...

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Detalles Bibliográficos
Autores principales: Chen, Xiao-cui, Wu, Dan, Wu, Hong-luan, Li, Hui-yuan, Yang, Chen, Su, Hong-yong, Liu, Ze-jian, Huang, Xiao-rong, Lu, Xing, Huang, Li-feng, Zhu, Shao-ping, Pan, Qing-jun, An, Ning, Liu, Hua-feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Lupus Nephritis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006817/
https://www.ncbi.nlm.nih.gov/pubmed/35414608
http://dx.doi.org/10.1136/lupus-2021-000611

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006817/
https://www.ncbi.nlm.nih.gov/pubmed/35414608
http://dx.doi.org/10.1136/lupus-2021-000611

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