Mfn2-mediated mitochondrial fusion alleviates doxorubicin-induced cardiotoxicity with enhancing its anticancer activity through metabolic switch

Imbalanced mitochondrial dynamics including inhibited mitochondrial fusion is associated with cardiac dysfunction as well as tumorigenesis. This study sought to explore the effects of promoting mitochondrial fusion on doxorubicin(Dox)-induced cardiotoxicity and its antitumor efficacy, with a focus o...

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Detalles Bibliográficos
Autores principales: Ding, Mingge, Shi, Rui, Cheng, Shuli, Li, Man, De, Dema, Liu, Chaoyang, Gu, Xiaoming, Li, Juan, Zhang, Shumiao, Jia, Min, Fan, Rong, Pei, Jianming, Fu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006862/
https://www.ncbi.nlm.nih.gov/pubmed/35413642
http://dx.doi.org/10.1016/j.redox.2022.102311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006862/
https://www.ncbi.nlm.nih.gov/pubmed/35413642
http://dx.doi.org/10.1016/j.redox.2022.102311

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