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Impact of Early ARV Initiation on Relative Proportions of Effector and Regulatory CD8 T Cell in Mesenteric Lymph Nodes and Peripheral Blood During Acute SIV Infection of Rhesus Macaques

CD8 T cells are key players in the clearance of human immunodeficiency virus (HIV)-infected cells, such that CD8 T-cell dysfunction contributes to viral persistence despite antiretroviral (ARV) therapy. Mesenteric lymph nodes (MLNs) are major sites of gut mucosal immunity. While different CD8 T cell...

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Detalles Bibliográficos
Autores principales: Yero, Alexis, Farnos, Omar, Clain, Julien, Zghidi-Abouzid, Ouafa, Rabezanahary, Henintsoa, Racine, Gina, Estaquier, Jérôme, Jenabian, Mohammad-Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006892/
https://www.ncbi.nlm.nih.gov/pubmed/35311550
http://dx.doi.org/10.1128/jvi.00255-22