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Altered Response Pattern following AZD5582 Treatment of SIV-Infected, ART-Suppressed Rhesus Macaque Infants

The “shock and kill” strategy for HIV-1 cure incorporates latency-reversing agents (LRA) in combination with interventions that aid the host immune system in clearing virally reactivated cells. LRAs have not yet been investigated in pediatric clinical or preclinical studies. Here, we evaluated an in...

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Detalles Bibliográficos
Autores principales: Bricker, Katherine M., Obregon-Perko, Veronica, Williams, Brianna, Oliver, Danielle, Uddin, Ferzan, Neja, Margaret, Hopkins, Louis, Dashti, Amir, Jean, Sherrie, Wood, Jennifer S., Ehnert, Stephanie, Liang, Shan, Vanderford, Thomas, Tharp, Gregory K., Bosinger, Steven E., Schauer, Amanda P., Mavigner, Maud, Cottrell, Mackenzie L., Margolis, David, Dunham, Richard M., Chahroudi, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9006931/
https://www.ncbi.nlm.nih.gov/pubmed/35293766
http://dx.doi.org/10.1128/jvi.01699-21