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Poly-phosphocholination of liposomes leads to highly-extended retention time in mice joints

Surface-attached layers of phosphatidylcholine (PC) lipid vesicles (liposomes) may reduce the friction coefficient μ (= force-to-slide/load) between the sliding surfaces down to μ ≈ 10(−3)–10(−4) up to tens of atm contact pressures, as high as those in the major joints (hips or knees). Such friction...

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Detalles Bibliográficos
Autores principales: Lin, Weifeng, Goldberg, Ronit, Klein, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007059/
https://www.ncbi.nlm.nih.gov/pubmed/35099493
http://dx.doi.org/10.1039/d1tb02346b