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Foscarnet-Type Inorganic-Organic Hybrid Nanoparticles for Effective Antiviral Therapy

[Image: see text] [ZrO](2+)[(FCN)(0.4)(OH)(0.8)](2–) and Gd(3+)[FCN](3–) inorganic-organic hybrid nanoparticles (IOH-NPs) are novel saline antiviral nanocarriers with foscarnet (FCN) as a drug anion. FCN as a pyrophosphate analogue serves as a prototype of a viral DNA polymerase inhibitor. FCN is us...

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Detalles Bibliográficos
Autores principales: Khorenko, Mikhail, Rand, Ulfert, Cicin-Sain, Luka, Feldmann, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007112/
https://www.ncbi.nlm.nih.gov/pubmed/35344659
http://dx.doi.org/10.1021/acsbiomaterials.2c00074