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Foscarnet-Type Inorganic-Organic Hybrid Nanoparticles for Effective Antiviral Therapy
[Image: see text] [ZrO](2+)[(FCN)(0.4)(OH)(0.8)](2–) and Gd(3+)[FCN](3–) inorganic-organic hybrid nanoparticles (IOH-NPs) are novel saline antiviral nanocarriers with foscarnet (FCN) as a drug anion. FCN as a pyrophosphate analogue serves as a prototype of a viral DNA polymerase inhibitor. FCN is us...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007112/ https://www.ncbi.nlm.nih.gov/pubmed/35344659 http://dx.doi.org/10.1021/acsbiomaterials.2c00074 |