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In Situ Programming of CAR T Cells

Gene therapy makes it possible to engineer chimeric antigen receptors (CARs) to create T cells that target specific diseases. However, current approaches require elaborate and expensive protocols to manufacture engineered T cells ex vivo, putting this therapy beyond the reach of many patients who mi...

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Detalles Bibliográficos
Autores principales: Parayath, Neha N., Stephan, Matthias T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007322/
https://www.ncbi.nlm.nih.gov/pubmed/33863239
http://dx.doi.org/10.1146/annurev-bioeng-070620-033348