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Neurochemical and cognitive changes precede structural abnormalities in the TgF344-AD rat model

Alzheimer’s disease is a progressive neurodegenerative disorder with a decades-long pre-symptomatic phase, substantiating the need for prodromal biomarker development and early intervention. To deconstruct the processes underlying disease progression and identify potential biomarkers, we used neuroi...

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Detalles Bibliográficos
Autores principales: Fowler, Caitlin F., Goerzen, Dana, Devenyi, Gabriel A., Madularu, Dan, Chakravarty, M. Mallar, Near, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007326/
https://www.ncbi.nlm.nih.gov/pubmed/35434622
http://dx.doi.org/10.1093/braincomms/fcac072