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Filling gaps in bacterial catabolic pathways with computation and high-throughput genetics
To discover novel catabolic enzymes and transporters, we combined high-throughput genetic data from 29 bacteria with an automated tool to find gaps in their catabolic pathways. GapMind for carbon sources automatically annotates the uptake and catabolism of 62 compounds in bacterial and archaeal geno...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007349/ https://www.ncbi.nlm.nih.gov/pubmed/35417463 http://dx.doi.org/10.1371/journal.pgen.1010156 |