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Long-read sequencing reveals complex patterns of wraparound transcription in polyomaviruses

Polyomaviruses (PyV) are ubiquitous pathogens that can cause devastating human diseases. Due to the small size of their genomes, PyV utilize complex patterns of RNA splicing to maximize their coding capacity. Despite the importance of PyV to human disease, their transcriptome architecture is poorly...

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Detalles Bibliográficos
Autores principales: Nomburg, Jason, Zou, Wei, Frost, Thomas C., Datta, Chandreyee, Vasudevan, Shobha, Starrett, Gabriel J., Imperiale, Michael J., Meyerson, Matthew, DeCaprio, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007360/
https://www.ncbi.nlm.nih.gov/pubmed/35363834
http://dx.doi.org/10.1371/journal.ppat.1010401