Exploring the Conformational Landscape and Stability of Aurora A Using Ion-Mobility Mass Spectrometry and Molecular Modeling

[Image: see text] Protein kinase inhibitors are highly effective in treating diseases driven by aberrant kinase signaling and as chemical tools to help dissect the cellular roles of kinase signaling complexes. Evaluating the effects of binding of small molecule inhibitors on kinase conformational dy...

Descripción completa

Detalles Bibliográficos
Autores principales: Tomlinson, Lauren J., Batchelor, Matthew, Sarsby, Joscelyn, Byrne, Dominic P., Brownridge, Philip J., Bayliss, Richard, Eyers, Patrick A., Eyers, Claire E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007459/
https://www.ncbi.nlm.nih.gov/pubmed/35099954
http://dx.doi.org/10.1021/jasms.1c00271

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007459/
https://www.ncbi.nlm.nih.gov/pubmed/35099954
http://dx.doi.org/10.1021/jasms.1c00271

Ejemplares similares