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Selectivity, Speciation, and Substrate Control in the Gold-Catalyzed Coupling of Indoles and Alkynes

[Image: see text] A convenient and mild protocol for the gold-catalyzed intermolecular coupling of substituted indoles with carbonyl-functionalized alkynes to give vinyl indoles is reported. This reaction affords 3-substituted indoles in high yield, and in contrast to the analogous reactions with si...

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Detalles Bibliográficos
Autores principales: Epton, Ryan G., Unsworth, William P., Lynam, Jason M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007570/
https://www.ncbi.nlm.nih.gov/pubmed/35431397
http://dx.doi.org/10.1021/acs.organomet.2c00035