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Aspirin’s effect on kinetic parameters of cells contributes to its role in reducing incidence of advanced colorectal adenomas, shown by a multiscale computational study

Aspirin intake has been shown to lead to significant protection against colorectal cancer, for example with an up to twofold reduction in colorectal adenoma incidence rates at higher doses. The mechanisms contributing to protection are not yet fully understood. While aspirin is an anti-inflammatory...

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Detalles Bibliográficos
Autores principales: Wang, Yifan, Boland, C Richard, Goel, Ajay, Wodarz, Dominik, Komarova, Natalia L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007589/
https://www.ncbi.nlm.nih.gov/pubmed/35416770
http://dx.doi.org/10.7554/eLife.71953