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Aspirin’s effect on kinetic parameters of cells contributes to its role in reducing incidence of advanced colorectal adenomas, shown by a multiscale computational study
Aspirin intake has been shown to lead to significant protection against colorectal cancer, for example with an up to twofold reduction in colorectal adenoma incidence rates at higher doses. The mechanisms contributing to protection are not yet fully understood. While aspirin is an anti-inflammatory...
Autores principales: | Wang, Yifan, Boland, C Richard, Goel, Ajay, Wodarz, Dominik, Komarova, Natalia L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007589/ https://www.ncbi.nlm.nih.gov/pubmed/35416770 http://dx.doi.org/10.7554/eLife.71953 |
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