APC/C (Cdh1p) and Slx5p/Slx8p ubiquitin ligases confer resistance to aminoglycoside hygromycin B in Saccharomyces cerevisiae

Multiple ubiquitin ligases with nuclear substrates promote regulated protein degradation and turnover of protein quality control (PQC) substrates. We hypothesized that two ubiquitin ligases with nuclear substrates – the anaphase-promoting complex/cyclosome with the Cdh1p substrate recognition factor...

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Detalles Bibliográficos
Autores principales: Doss, Ellen M., Tragesser-Tiña, Mary E., Huang, Yanru, Smaldino, Philip J., True, Jason D., Kalinski, Ashley L., Rubenstein, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007615/
https://www.ncbi.nlm.nih.gov/pubmed/35622489
http://dx.doi.org/10.17912/micropub.biology.000547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007615/
https://www.ncbi.nlm.nih.gov/pubmed/35622489
http://dx.doi.org/10.17912/micropub.biology.000547

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