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APC/C (Cdh1p) and Slx5p/Slx8p ubiquitin ligases confer resistance to aminoglycoside hygromycin B in Saccharomyces cerevisiae
Multiple ubiquitin ligases with nuclear substrates promote regulated protein degradation and turnover of protein quality control (PQC) substrates. We hypothesized that two ubiquitin ligases with nuclear substrates – the anaphase-promoting complex/cyclosome with the Cdh1p substrate recognition factor...
Autores principales: | Doss, Ellen M., Tragesser-Tiña, Mary E., Huang, Yanru, Smaldino, Philip J., True, Jason D., Kalinski, Ashley L., Rubenstein, Eric M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007615/ https://www.ncbi.nlm.nih.gov/pubmed/35622489 http://dx.doi.org/10.17912/micropub.biology.000547 |
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