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Hyper-Methylated Hub Genes of T-Cell Receptor Signaling Predict a Poor Clinical Outcome in Lung Adenocarcinoma

BACKGROUND: Immune checkpoint inhibitors (ICIs) emerge as the first-line treatment of lung adenocarcinoma (LUAD); selection of subpopulations acquiring clinical benefit is required. Associations between epigenetic modulation of tumor microenvironment (TME) and clinical outcome are far from clear. We...

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Detalles Bibliográficos
Autores principales: Hu, Zixin, Xue, Chongxiang, Zheng, Jiabin, Lu, Xingyu, Li, Jia, Dong, Huijing, Yu, Yixuan, Zhang, Xu, Tan, Kexin, Cui, Huijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007647/
https://www.ncbi.nlm.nih.gov/pubmed/35432532
http://dx.doi.org/10.1155/2022/5426887