Cargando…

Hyper-Methylated Hub Genes of T-Cell Receptor Signaling Predict a Poor Clinical Outcome in Lung Adenocarcinoma

BACKGROUND: Immune checkpoint inhibitors (ICIs) emerge as the first-line treatment of lung adenocarcinoma (LUAD); selection of subpopulations acquiring clinical benefit is required. Associations between epigenetic modulation of tumor microenvironment (TME) and clinical outcome are far from clear. We...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hu, Zixin, Xue, Chongxiang, Zheng, Jiabin, Lu, Xingyu, Li, Jia, Dong, Huijing, Yu, Yixuan, Zhang, Xu, Tan, Kexin, Cui, Huijuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007647/ https://www.ncbi.nlm.nih.gov/pubmed/35432532 http://dx.doi.org/10.1155/2022/5426887

Ejemplares similares

Radiation induced lung injury (RILI) after postoperative intensity modulated proton therapy (IMPT) in a patient with stage III locally advanced lung adenocarcinoma: a case report
por: Hu, Zixin, et al.
Publicado: (2022)

Efficacy and Safety of Immune Checkpoint Inhibitors in Patients with Cancer and Hepatitis B or C: A Systematic Review and Meta-Analysis
por: Dong, Huijing, et al.
Publicado: (2023)

Long-term survival in extensive-stage small-cell lung cancer treated with different immune checkpoint inhibitors in multiple-line therapies: A case report and literature review
por: Zhang, Xu, et al.
Publicado: (2022)

Microsatellite instability-related prognostic risk score (MSI-pRS) defines a subset of lung squamous cell carcinoma (LUSC) patients with genomic instability and poor clinical outcome
por: Hu, Zixin, et al.
Publicado: (2023)

Association Between Efficacy of Immune Checkpoint Inhibitors and Sex: An Updated Meta-Analysis on 21 Trials and 12,675 Non-Small Cell Lung Cancer Patients
por: Xue, Chongxiang, et al.
Publicado: (2021)

Key microRNAs and hub genes associated with poor prognosis in lung adenocarcinoma
por: Ye, Guan-Chao, et al.
Publicado: (2021)

Changes of IL-6 And IFN-γ before and after the adverse events related to immune checkpoint inhibitors: A retrospective study
por: Zhang, Xu, et al.
Publicado: (2022)

Immune Checkpoint Inhibitors in the Treatment of Patients With Cancer and Preexisting Psoriasis: A Systematic Review and Meta-Analysis of Observational Studies
por: Yu, Yixuan, et al.
Publicado: (2022)

The incidence of pseudoprogressive disease associated with programmed cell death 1/programmed cell death ligand 1 inhibitors: A meta-analysis
por: Zhang, Jingyi, et al.
Publicado: (2021)

Lung Adenocarcinoma with Paraneoplastic Hyper-Eosinophilia Not Responding To Pembrolizumab
por: Wehbe, Hisham, et al.
Publicado: (2021)

Exploration of the hub genes and miRNAs in lung adenocarcinoma
por: Zhai, Yuanyuan, et al.
Publicado: (2019)

Weighted gene co-expression network analysis of hub genes in lung adenocarcinoma
por: Luo, Xuan, et al.
Publicado: (2021)

TGFBI Promoter Methylation is Associated with Poor Prognosis in Lung Adenocarcinoma Patients
por: Seok, Yangki, et al.
Publicado: (2019)

Effects of hub genes on the clinicopathological and prognostic features of lung adenocarcinoma
por: Yu, Dong-Hu, et al.
Publicado: (2020)

Topical Zhiyang Pingfu Liquid for Moderate to Severe Skin Rash Associated With EGFRIs: A double-blinded randomized controlled trial
por: Zhang, Jingyi, et al.
Publicado: (2022)

Rich can get poor: conversion of hub to non-hub proteins
por: Tun, Kyaw, et al.
Publicado: (2009)

Exploration and validation of hub genes in lung adenocarcinoma based on bioinformatics analysis
por: Zeng, Changyi, et al.
Publicado: (2022)

Effects of autophagy-associated genes on the prognosis for lung adenocarcinoma
por: Chen, Chongxiang, et al.
Publicado: (2020)

XXYLT1 methylation contributes to the occurrence of lung adenocarcinoma: Methylation and lung adenocarcinoma
por: Zeng, Hui, et al.
Publicado: (2021)

Identification of Hub Genes in Pancreatic Ductal Adenocarcinoma Using Bioinformatics Analysis
por: Wang, Congcong, et al.
Publicado: (2021)

Increased resistin suggests poor prognosis and promotes development of lung adenocarcinoma
por: Zhao, Cui-Cui, et al.
Publicado: (2018)

Identification of Hub Genes for Early Diagnosis and Predicting Prognosis in Colon Adenocarcinoma
por: Xu, Shuo, et al.
Publicado: (2022)

Identification of hub genes and construction of transcriptional regulatory network for the progression of colon adenocarcinoma hub genes and TF regulatory network of colon adenocarcinoma
por: Wei, Shuxun, et al.
Publicado: (2019)

Gene–microRNA Network Analysis Identified Seven Hub Genes in Association with Progression and Prognosis in Non-Small Cell Lung Cancer
por: Yang, Zhiyuan, et al.
Publicado: (2022)

[Retracted] Increased resistin suggests poor prognosis and promotes development of lung adenocarcinoma
por: Zhao, Cui-Cui, et al.
Publicado: (2023)

Paraneoplastic Hypereosinophilia in Poorly Differentiated Adenocarcinoma of the Lung
por: Ream, Sarah, et al.
Publicado: (2023)

High SERPINH1 expression predicts poor prognosis in lung adenocarcinoma
por: Zhang, Hailing, et al.
Publicado: (2022)

Integration of gene profile to explore the hub genes of lung adenocarcinoma: A quasi-experimental study
por: Hua, Peiyan, et al.
Publicado: (2020)

Identification of hub driving genes and regulators of lung adenocarcinoma based on the gene Co-expression network
por: Xu, Zihao, et al.
Publicado: (2020)

Identification of Hub Genes in Colorectal Adenocarcinoma by Integrated Bioinformatics
por: Liu, Yang, et al.
Publicado: (2022)

Bioinformatic analysis of potential hub genes in gastric adenocarcinoma
por: Liu, Hao, et al.
Publicado: (2021)

CMTM6 is highly expressed in lung adenocarcinoma and can be used as a biomarker of a poor diagnosis
por: Jia, Daqi, et al.
Publicado: (2023)

High-resolution Nanopore methylome-maps reveal random hyper-methylation at CpG-poor regions as driver of chemoresistance in leukemias
por: Magi, Alberto, et al.
Publicado: (2023)

Overexpression of eIF3D in Lung Adenocarcinoma Is a New Independent Prognostic Marker of Poor Survival
por: Wang, Dan, et al.
Publicado: (2019)

AC099850.3/NCAPG Axis Predicts Poor Prognosis and is Associated with Resistance to EGFR Tyrosine-Kinase Inhibitors in Lung Adenocarcinoma
por: Bao, Jiaqi, et al.
Publicado: (2022)

Downregulation of NMI promotes tumor growth and predicts poor prognosis in human lung adenocarcinomas
por: Wang, Jingshu, et al.
Publicado: (2017)

Weighted gene coexpression network analysis identifies hub genes related to KRAS mutant lung adenocarcinoma
por: Dai, Dongjun, et al.
Publicado: (2020)

A Novel circRNA–miRNA–mRNA Hub Regulatory Network in Lung Adenocarcinoma
por: Zuo, Haiwei, et al.
Publicado: (2021)

An integrated analysis of prognostic and immune infiltrates for hub genes as potential survival indicators in patients with lung adenocarcinoma
por: Xu, Zhiyun, et al.
Publicado: (2022)

Identification of Hub Genes of Lung Adenocarcinoma Based on Weighted Gene Co-Expression Network in Chinese Population
por: Xie, Yuning, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5a8md2m85o51ni67idkh23lsp8