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USP7 Attenuates Endoplasmic Reticulum Stress and NF-κB Signaling to Modulate Chondrocyte Proliferation, Apoptosis, and Inflammatory Response under Inflammation

The purpose of this research was to observe the functions and mechanisms of ubiquitin-specific peptidase 7 (USP7) on chondrocytes under tumor necrosis factor alpha- (TNF-α-) induced inflammation. Knee osteoarthritis (OA) models of mice were constructed by anterior cruciate ligament transection. The...

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Detalles Bibliográficos
Autores principales: Dong, Xiaofei, Yang, Chang, Luo, Yao, Dong, Wei, Xu, Xiaoxiao, Wu, Yanru, Wang, Jiawei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007692/
https://www.ncbi.nlm.nih.gov/pubmed/35432716
http://dx.doi.org/10.1155/2022/1835900