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Improved Precision-Cut Liver Slice Cultures for Testing Drug-Induced Liver Fibrosis

In vitro models of human liver disease often fail to mimic the complex 3D structures and cellular organizations found in vivo. Precision cut liver slices (PCLS) retain the complex physiological architecture of the native liver and therefore could be an exceptional in vitro liver model. However, the...

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Detalles Bibliográficos
Autores principales: Dewyse, Liza, De Smet, Vincent, Verhulst, Stefaan, Eysackers, Nathalie, Kunda, Rastislav, Messaoudi, Nouredin, Reynaert, Hendrik, van Grunsven, Leo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007724/
https://www.ncbi.nlm.nih.gov/pubmed/35433753
http://dx.doi.org/10.3389/fmed.2022.862185