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Capturing a rhodopsin receptor signalling cascade across a native membrane

G protein-coupled receptors (GPCRs) are cell-surface receptors that respond to various stimuli to induce signalling pathways across cell membranes. Recent progress has yielded atomic structures of key intermediates(1,2) and roles for lipids in signalling(3,4). However, capturing signalling events of...

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Detalles Bibliográficos
Autores principales: Chen, Siyun, Getter, Tamar, Salom, David, Wu, Di, Quetschlich, Daniel, Chorev, Dror S., Palczewski, Krzysztof, Robinson, Carol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007743/
https://www.ncbi.nlm.nih.gov/pubmed/35388214
http://dx.doi.org/10.1038/s41586-022-04547-x