Oscillatory calcium release and sustained store-operated oscillatory calcium signaling prevents differentiation of human oligodendrocyte progenitor cells

Endogenous remyelination in demyelinating diseases such as multiple sclerosis is contingent upon the successful differentiation of oligodendrocyte progenitor cells (OPCs). Signaling via the Gα(q)-coupled muscarinic receptor (M(1/3)R) inhibits human OPC differentiation and impairs endogenous remyelin...

Descripción completa

Detalles Bibliográficos
Autores principales: Seidman, Richard A., Khattab, Heba, Polanco, Jessie J., Broome, Jacqueline E., Sim, Fraser J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007940/
https://www.ncbi.nlm.nih.gov/pubmed/35418597
http://dx.doi.org/10.1038/s41598-022-10095-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007940/
https://www.ncbi.nlm.nih.gov/pubmed/35418597
http://dx.doi.org/10.1038/s41598-022-10095-1

Ejemplares similares