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Oscillatory calcium release and sustained store-operated oscillatory calcium signaling prevents differentiation of human oligodendrocyte progenitor cells
Endogenous remyelination in demyelinating diseases such as multiple sclerosis is contingent upon the successful differentiation of oligodendrocyte progenitor cells (OPCs). Signaling via the Gα(q)-coupled muscarinic receptor (M(1/3)R) inhibits human OPC differentiation and impairs endogenous remyelin...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007940/ https://www.ncbi.nlm.nih.gov/pubmed/35418597 http://dx.doi.org/10.1038/s41598-022-10095-1 |