Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3

Human aldehyde dehydrogenase (ALDH) participates in the oxidative stress response and retinoid metabolism, being involved in several diseases, including cancer, diabetes and obesity. The ALDH1A3 isoform has recently elicited wide interest because of its potential use as a cancer stem cell biomarker...

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Detalles Bibliográficos
Autores principales: Castellví, Albert, Pequerul, Raquel, Barracco, Vito, Juanhuix, Judith, Parés, Xavier, Farrés, Jaume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007972/
https://www.ncbi.nlm.nih.gov/pubmed/35418200
http://dx.doi.org/10.1038/s42003-022-03311-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007972/
https://www.ncbi.nlm.nih.gov/pubmed/35418200
http://dx.doi.org/10.1038/s42003-022-03311-1

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