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Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3
Human aldehyde dehydrogenase (ALDH) participates in the oxidative stress response and retinoid metabolism, being involved in several diseases, including cancer, diabetes and obesity. The ALDH1A3 isoform has recently elicited wide interest because of its potential use as a cancer stem cell biomarker...
Autores principales: | Castellví, Albert, Pequerul, Raquel, Barracco, Vito, Juanhuix, Judith, Parés, Xavier, Farrés, Jaume |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007972/ https://www.ncbi.nlm.nih.gov/pubmed/35418200 http://dx.doi.org/10.1038/s42003-022-03311-1 |
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