Cargando…

CHD7 regulates bone-fat balance by suppressing PPAR-γ signaling

Chromodomain helicase DNA-binding protein 7 (CHD7), an ATP-dependent eukaryotic chromatin remodeling enzyme, is essential for the development of organs. The mutation of CHD7 is the main cause of CHARGE syndrome, but its function and mechanism in skeletal system remain unclear. Here, we show conditio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Caojie, Xiong, Qiuchan, Li, Qiwen, Lin, Weimin, Jiang, Shuang, Zhang, Danting, Wang, Yuan, Duan, Xiaobo, Gong, Ping, Kang, Ning
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9007978/ https://www.ncbi.nlm.nih.gov/pubmed/35418650 http://dx.doi.org/10.1038/s41467-022-29633-6

Ejemplares similares

CHD7 Regulates Osteogenic Differentiation of Human Dental Follicle Cells via PTH1R Signaling
por: Liu, Caojie, et al.
Publicado: (2020)

Advances in Chromodomain Helicase DNA-Binding (CHD) Proteins Regulating Stem Cell Differentiation and Human Diseases
por: Liu, Caojie, et al.
Publicado: (2021)

PPARγ and PPARα synergize to induce robust browning of white fat in vivo
por: Kroon, Tobias, et al.
Publicado: (2020)

A role for CNS PPARγ in the regulation of energy balance
por: Ryan, Karen K., et al.
Publicado: (2011)

Rosiglitazone activation of PPARγ suppresses fractalkine signaling
por: Wan, Yihong, et al.
Publicado: (2010)

Metformin promotes osteogenic differentiation and prevents hyperglycaemia-induced osteoporosis by suppressing PPARγ expression: Metformin prevents osteoporosis by suppressing PPARγ
por: Zheng, Lifeng, et al.
Publicado: (2023)

Quantitative PPARγ expression affects the balance between tolerance and immunity
por: Liu, Ya-Hui, et al.
Publicado: (2016)

β-arrestin-1 contributes to brown fat function and directly interacts with PPARα and PPARγ
por: Wang, Congcong, et al.
Publicado: (2016)

PPARγ activation modulates the balance of peritoneal macrophage populations to suppress ovarian tumor growth and tumor-induced immunosuppression
por: Prat, Mélissa, et al.
Publicado: (2023)

METTL3-mediated m(6)A RNA methylation regulates dorsal lingual epithelium homeostasis
por: Xiong, Qiuchan, et al.
Publicado: (2022)

Acetylation of PPARγ in macrophages promotes visceral fat degeneration in obesity
por: Aaron, Nicole, et al.
Publicado: (2022)

Shockwaves Suppress Adipocyte Differentiation via Decrease in PPARγ
por: Cho, Wonkyoung, et al.
Publicado: (2020)

PPARγ/mTOR signalling: striking the right balance in cartilage homeostasis
por: Dell'Accio, Francesco, et al.
Publicado: (2015)

PPARγ2(Pro12Ala) Polymorphism and Human Health
por: He, Weimin
Publicado: (2009)

Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8
por: Marie, Corentine, et al.
Publicado: (2018)

The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities
por: Manning, Benjamin J., et al.
Publicado: (2017)

Abstract 12: Development of Compact Fat Graft by Modulating PPARγ Neddylation
por: Kim, Il-Kug, et al.
Publicado: (2019)

PPARγ in Neuroblastoma
por: Peri, Alessandro, et al.
Publicado: (2008)

Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases
por: Kulkarni, Ajit A., et al.
Publicado: (2012)

PPARγ activation suppresses chondrocyte ferroptosis through mitophagy in osteoarthritis
por: Xue, Xiang, et al.
Publicado: (2023)

CHD7 in oocytes is essential for female fertility
por: Cheng, Jie, et al.
Publicado: (2022)

Mapping the immune microenvironment for mandibular alveolar bone homeostasis at single-cell resolution
por: Lin, Weimin, et al.
Publicado: (2021)

The contrasting roles of PPARδ and PPARγ in regulating the metabolic switch between oxidation and storage of fats in white adipose tissue
por: Roberts, Lee D, et al.
Publicado: (2011)

Ablation of PPARγ in subcutaneous fat exacerbates age‐associated obesity and metabolic decline
por: Xu, Lingyan, et al.
Publicado: (2018)

MiR130b-Regulation of PPARγ Coactivator- 1α Suppresses Fat Metabolism in Goat Mammary Epithelial Cells
por: Chen, Zhi, et al.
Publicado: (2015)

The role and function of PPARγ in bladder cancer
por: Peng, Tianchen, et al.
Publicado: (2020)

Do PPARγ Ligands Suppress the Growth of Cholangiocarcinoma or the Cholangiohepatitis Induced by the Tumor?
por: Suzuki, Satoru, et al.
Publicado: (2008)

SIRT6 transcriptionally regulates fatty acid transport by suppressing PPARγ
por: Khan, Danish, et al.
Publicado: (2021)

PPARγ and Apoptosis in Cancer
por: Elrod, Heath A., et al.
Publicado: (2008)

PPARγ, neuroinflammation, and disease
por: Mrak, Robert E, et al.
Publicado: (2004)

Nutraceuticals as Ligands of PPARγ
por: Penumetcha, Meera, et al.
Publicado: (2012)

PPARγ and Cognitive Performance
por: d’Angelo, Michele, et al.
Publicado: (2019)

The CHD8/CHD7/Kismet family links blood-brain barrier glia and serotonin to ASD-associated sleep defects
por: Coll-Tané, Mireia, et al.
Publicado: (2021)

Phosphorylation of PPARγ Affects the Collective Motions of the PPARγ-RXRα-DNA Complex
por: Lemkul, Justin A., et al.
Publicado: (2015)

Genetic and diet effects on Ppar-α and Ppar-γ signaling pathways in the Berlin Fat Mouse Inbred line with genetic predisposition for obesity
por: Wagener, Asja, et al.
Publicado: (2010)

PPARγ and PPARδ as Modulators of Neoplasia and Cell Fate
por: Glazer, Robert I., et al.
Publicado: (2008)

Chromatin Remodeling in Development and Disease: Focus on CHD7
por: Martin, Donna M.
Publicado: (2010)

SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARγ2
por: Akter, Fatema, et al.
Publicado: (2021)

Methylome, transcriptome, and PPARγ cistrome analyses reveal two epigenetic transitions in fat cells
por: Takada, Hitomi, et al.
Publicado: (2014)

High Fat Diet Upregulates Fatty Acid Oxidation and Ketogenesis via Intervention of PPAR- γ
por: Sikder, Kunal, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_j65lspvckm01kmbh51ntg304pt