TGF-β induces GBM mesenchymal transition through upregulation of CLDN4 and nuclear translocation to activate TNF-α/NF-κB signal pathway

Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor. The unregulated expression of Claudin-4 (CLDN4) plays an important role in tumor progression. However, the biological role of CLDN4 in GBM is still unknown. This study aimed to determine whether CLDN4 mediates glioma...

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Detalles Bibliográficos
Autores principales: Yan, Tengfeng, Tan, Yinqiu, Deng, Gang, Sun, Zhiqiang, Liu, Baohui, Wang, Yixuan, Yuan, Fanen, Sun, Qian, Hu, Ping, Gao, Lun, Tian, Daofeng, Chen, Qianxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008023/
https://www.ncbi.nlm.nih.gov/pubmed/35418179
http://dx.doi.org/10.1038/s41419-022-04788-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008023/
https://www.ncbi.nlm.nih.gov/pubmed/35418179
http://dx.doi.org/10.1038/s41419-022-04788-8

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