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The lipophilic cyclic peptide cyclosporin A induces aggregation of gel-forming mucins
Cyclic peptides are good candidates for orally delivered therapeutics, however, issues remain in their development due to low intestinal permeability. Although some of the biological factors have been reported that regulate intestinal permeation of cyclic peptides, the influence of the mucus barrier...
Autores principales: | Kishimoto, Hisanao, Ridley, Caroline, Thornton, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008041/ https://www.ncbi.nlm.nih.gov/pubmed/35418571 http://dx.doi.org/10.1038/s41598-022-10125-y |
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