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Estradiol inhibits HIV-1(BaL) infection and induces CFL1 expression in peripheral blood mononuclear cells and endocervical mucosa

An inhibitory effect of estradiol (E2) on HIV-1 infection was suggested by several reports. We previously identified increased gene expression of actin-binding protein cofilin 1 (CFL1) in endocervix in the E2-dominated proliferative phase of the menstrual cycle. Actin cytoskeleton has an integral ro...

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Detalles Bibliográficos
Autores principales: Verma, N., Mukhopadhyay, S., Barnable, P., Plagianos, M. G., Teleshova, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008051/
https://www.ncbi.nlm.nih.gov/pubmed/35418661
http://dx.doi.org/10.1038/s41598-022-10163-6