Homology-based repair induced by CRISPR-Cas nucleases in mammalian embryo genome editing

Recent advances in genome editing, especially CRISPR-Cas nucleases, have revolutionized both laboratory research and clinical therapeutics. CRISPR-Cas nucleases, together with the DNA damage repair pathway in cells, enable both genetic diversification by classical non-homologous end joining (c-NHEJ)...

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Detalles Bibliográficos
Autores principales: Zhang, Xiya, Li, Tao, Ou, Jianping, Huang, Junjiu, Liang, Puping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008090/
https://www.ncbi.nlm.nih.gov/pubmed/33945139
http://dx.doi.org/10.1007/s13238-021-00838-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008090/
https://www.ncbi.nlm.nih.gov/pubmed/33945139
http://dx.doi.org/10.1007/s13238-021-00838-7

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