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Immunogenicity of convalescent and vaccinated sera against clinical isolates of ancestral SARS-CoV-2, Beta, Delta, and Omicron variants

BACKGROUND: SARS-CoV-2 Omicron variant of concern (VOC) has evolved multiple mutations within the spike protein, raising concerns of increased antibody evasion. In this study, we assessed the neutralization potential of COVID-19 convalescent sera and sera from vaccinated individuals against ancestra...

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Detalles Bibliográficos
Autores principales: Banerjee, Arinjay, Lew, Jocelyne, Kroeker, Andrea, Baid, Kaushal, Aftanas, Patryk, Nirmalarajah, Kuganya, Maguire, Finlay, Kozak, Robert, McDonald, Ryan, Lang, Amanda, Gerdts, Volker, Straus, Sharon E., Gilbert, Lois, Li, Angel Xinliu, Mozafarihashjin, Mohammad, Walmsley, Sharon, Gingras, Anne-Claude, Wrana, Jeffrey L., Mazzulli, Tony, Colwill, Karen, McGeer, Allison J., Mubareka, Samira, Falzarano, Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008123/
https://www.ncbi.nlm.nih.gov/pubmed/35437520
http://dx.doi.org/10.1016/j.medj.2022.04.002