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Algorithmic multiscale analysis for the FcRn mediated regulation of antibody PK in human
A demonstration is provided on how algorithmic asymptotic analysis of multi-scale pharmacokinetics (PK) systems can provide (1) system level understanding and (2) predictions on the response of the model when parameters vary. Being algorithmic, this type of analysis is not hindered by the size or co...
Autores principales: | Patsatzis, Dimitris G., Wu, Shengjia, Shah, Dhaval K., Goussis, Dimitris A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008124/ https://www.ncbi.nlm.nih.gov/pubmed/35418134 http://dx.doi.org/10.1038/s41598-022-09846-x |
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