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PAD4 Immunization Triggers Anti-Citrullinated Peptide Antibodies in Normal Mice: Analysis With Peptide Arrays

The critical immunological event in rheumatoid arthritis (RA) is the production of antibodies to citrullinated proteins (ACPAs), ie proteins on which arginines have been transformed into citrullines by peptidyl arginine deiminases (PAD). In C3H mice, immunization with PAD4 triggers the production of...

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Detalles Bibliográficos
Autores principales: Hemon, Marie F., Lambert, Nathalie C., Arnoux, Fanny, Roudier, Jean, Auger, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008206/
https://www.ncbi.nlm.nih.gov/pubmed/35432329
http://dx.doi.org/10.3389/fimmu.2022.840035