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Comparison of the Anti-inflammatory Properties of Two Nicotinic Acetylcholine Receptor Ligands, Phosphocholine and pCF3-diEPP

Activation of nicotinic acetylcholine receptors (nAChRs) expressed by innate immune cells can attenuate pro-inflammatory responses. Silent nAChR agonists, which down-modulate inflammation but have little or no ionotropic activity, are of outstanding clinical interest for the prevention and therapy o...

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Detalles Bibliográficos
Autores principales: Richter, Katrin, Papke, Roger L., Stokes, Clare, Roy, Danika C., Espinosa, Eduardo S., Wolf, Philipp M. K., Hecker, Andreas, Liese, Juliane, Singh, Vijay K., Padberg, Winfried, Schlüter, Klaus-Dieter, Rohde, Marius, McIntosh, J. Michael, Morley, Barbara J., Horenstein, Nicole A., Grau, Veronika, Simard, Alain R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008208/
https://www.ncbi.nlm.nih.gov/pubmed/35431807
http://dx.doi.org/10.3389/fncel.2022.779081