Generating Ensembles of Dynamic Misfolding Proteins

The early stages of protein misfolding and aggregation involve disordered and partially folded protein conformers that contain a high degree of dynamic disorder. These dynamic species may undergo large-scale intra-molecular motions of intrinsically disordered protein (IDP) precursors, or flexible, l...

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Detalles Bibliográficos
Autores principales: Karamanos, Theodoros K., Kalverda, Arnout P., Radford, Sheena E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008329/
https://www.ncbi.nlm.nih.gov/pubmed/35431773
http://dx.doi.org/10.3389/fnins.2022.881534

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008329/
https://www.ncbi.nlm.nih.gov/pubmed/35431773
http://dx.doi.org/10.3389/fnins.2022.881534

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