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Generating Ensembles of Dynamic Misfolding Proteins

The early stages of protein misfolding and aggregation involve disordered and partially folded protein conformers that contain a high degree of dynamic disorder. These dynamic species may undergo large-scale intra-molecular motions of intrinsically disordered protein (IDP) precursors, or flexible, l...

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Detalles Bibliográficos
Autores principales:	Karamanos, Theodoros K., Kalverda, Arnout P., Radford, Sheena E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008329/ https://www.ncbi.nlm.nih.gov/pubmed/35431773 http://dx.doi.org/10.3389/fnins.2022.881534

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