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N-Glycosylation at Asn291 Stabilizes TIM-4 and Promotes the Metastasis of NSCLC

T-cell immunoglobulin domain and mucin domain 4 (TIM-4) is a transmembrane protein that promotes epithelial-mesenchymal transition (EMT), migration and invasion of non-small cell lung cancer (NSCLC) cells. Most transmembrane proteins are modified by N-glycosylation and the importance of protein N-gl...

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Detalles Bibliográficos
Autores principales: Chen, Siyuan, Wang, Yuzhen, Liu, Wen, Liang, Yan, Wang, Yingchun, Wu, Zhuanchang, Xu, Liyun, Liang, Xiaohong, Ma, Chunhong, Gao, Lifen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9008408/
https://www.ncbi.nlm.nih.gov/pubmed/35433445
http://dx.doi.org/10.3389/fonc.2022.730530